HCSGD entry for FGF18

1. General information

Official gene symbolFGF18
Entrez ID8817
Gene full namefibroblast growth factor 18
Other gene symbolsFGF-18 ZFGF5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001525AngiogenesisIEAbiological_process
GO:0001957Intramembranous ossificationIEAbiological_process
GO:0001958Endochondral ossificationIEAbiological_process
GO:0002063Chondrocyte developmentIEAbiological_process
GO:0005105Type 1 fibroblast growth factor receptor bindingIDAmolecular_function
GO:0005111Type 2 fibroblast growth factor receptor bindingIDAmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceTAScellular_component
GO:0005730NucleolusIDAcellular_component
GO:0007165Signal transductionTASbiological_process
GO:0007173Epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0007399Nervous system developmentIEAbiological_process
GO:0008083Growth factor activityIEAmolecular_function
GO:0008284Positive regulation of cell proliferationIEAbiological_process
GO:0008286Insulin receptor signaling pathwayTASbiological_process
GO:0008543Fibroblast growth factor receptor signaling pathwayTASbiological_process
GO:0009653Anatomical structure morphogenesisTASbiological_process
GO:0030324Lung developmentIEAbiological_process
GO:0030949Positive regulation of vascular endothelial growth factor receptor signaling pathwayIEAbiological_process
GO:0032332Positive regulation of chondrocyte differentiationIEAbiological_process
GO:0038095Fc-epsilon receptor signaling pathwayTASbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0048015Phosphatidylinositol-mediated signalingTASbiological_process
GO:0070374Positive regulation of ERK1 and ERK2 cascadeIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.20395807530.85865598190.87120748131.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1696909901
GSE13712_SHEARDown-1.0779952583
GSE13712_STATICUp0.0129635906
GSE19018Up0.0868139200
GSE19899_A1Down-0.0183789125
GSE19899_A2Up0.3702288162
PubMed_21979375_A1Up0.1956386227
PubMed_21979375_A2Up0.1811151032
GSE35957Down-0.0173158937
GSE36640Up0.1324957782
GSE54402Up0.1762971248
GSE9593Up0.0860106157
GSE43922Up0.1394525835
GSE24585Down-0.0988144522
GSE37065Up0.2238362439
GSE28863_A1Up0.0591050536
GSE28863_A2Up0.1994779423
GSE28863_A3Up0.4007430548
GSE28863_A4Up0.0901481880
GSE48662Down-0.0682236552

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.