HCSGD entry for CDKL1
1. General information
| Official gene symbol | CDKL1 |
|---|---|
| Entrez ID | 8814 |
| Gene full name | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| Other gene symbols | KKIALRE P42 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004672 | Protein kinase activity | IEA | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0004693 | Cyclin-dependent protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006468 | Protein phosphorylation | TAS | biological_process |
| GO:0007049 | Cell cycle | TAS | biological_process |
| GO:0007507 | Heart development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8586941416 | 0.1229301356 | 0.9999902473 | 0.6736714762 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2830206736 |
| GSE13712_SHEAR | Up | 0.2657542186 |
| GSE13712_STATIC | Down | -0.2778166547 |
| GSE19018 | Down | -0.1307193275 |
| GSE19899_A1 | Up | 0.0298040587 |
| GSE19899_A2 | Down | -0.8310659670 |
| PubMed_21979375_A1 | Up | 0.0480232447 |
| PubMed_21979375_A2 | Down | -0.2163357592 |
| GSE35957 | Down | -0.1366249851 |
| GSE36640 | Down | -0.3957943888 |
| GSE54402 | Down | -0.2732518449 |
| GSE9593 | Down | -0.0776245126 |
| GSE43922 | Down | -0.1915447151 |
| GSE24585 | Down | -0.2630323092 |
| GSE37065 | Up | 0.0773411062 |
| GSE28863_A1 | Down | -0.3257512373 |
| GSE28863_A2 | Down | -0.1160626002 |
| GSE28863_A3 | Down | -0.1782134358 |
| GSE28863_A4 | Up | 0.2740544511 |
| GSE48662 | Up | 0.4308149168 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
