HCSGD entry for IL1RL2


1. General information

Official gene symbolIL1RL2
Entrez ID8808
Gene full nameinterleukin 1 receptor-like 2
Other gene symbolsIL-1Rrp2 IL-36R IL1R-rp2 IL1RRP2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004908Interleukin-1 receptor activityIEA TASmolecular_function
GO:0004909Interleukin-1, Type I, activating receptor activityIEAmolecular_function
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006968Cellular defense responseTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0032755Positive regulation of interleukin-6 productionIEAbiological_process
GO:0045582Positive regulation of T cell differentiationIEAbiological_process
GO:0050727Regulation of inflammatory responseIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.33013496830.90926217850.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0678124564
GSE13712_SHEARUp0.0572484520
GSE13712_STATICUp0.1151996204
GSE19018Up0.1024573372
GSE19899_A1Down-0.0651029780
GSE19899_A2Up0.2329056333
PubMed_21979375_A1Up0.1106231946
PubMed_21979375_A2Up0.0156117189
GSE35957Down-0.0962180712
GSE36640Up0.0258813752
GSE54402Up0.1116377487
GSE9593Up0.1866598486
GSE43922Up0.1971584788
GSE24585Up0.0423797446
GSE37065Up0.3380458185
GSE28863_A1Up0.2891308054
GSE28863_A2Down-0.0294353841
GSE28863_A3Up0.1838469906
GSE28863_A4Down-0.1039675753
GSE48662Down-0.0146528630

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.