HCSGD entry for SUCLG2
1. General information
| Official gene symbol | SUCLG2 |
|---|---|
| Entrez ID | 8801 |
| Gene full name | succinate-CoA ligase, GDP-forming, beta subunit |
| Other gene symbols | GBETA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0004776 | Succinate-CoA ligase (GDP-forming) activity | NAS | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0006099 | Tricarboxylic acid cycle | IEA TAS | biological_process |
| GO:0006104 | Succinyl-CoA metabolic process | NAS | biological_process |
| GO:0006105 | Succinate metabolic process | IEA | biological_process |
| GO:0019003 | GDP binding | IEA | molecular_function |
| GO:0044237 | Cellular metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0045244 | Succinate-CoA ligase complex (GDP-forming) | IEA | cellular_component |
| GO:0046982 | Protein heterodimerization activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9835281676 | 0.0116847080 | 0.9999902473 | 0.2133600832 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4103906841 |
| GSE13712_SHEAR | Down | -0.0635447895 |
| GSE13712_STATIC | Up | 0.0614451548 |
| GSE19018 | Up | 0.1359096181 |
| GSE19899_A1 | Down | -0.5678602103 |
| GSE19899_A2 | Down | -0.6839783524 |
| PubMed_21979375_A1 | Down | -1.1247001512 |
| PubMed_21979375_A2 | Down | -1.0449585692 |
| GSE35957 | Down | -0.1904537873 |
| GSE36640 | Down | -0.5121415758 |
| GSE54402 | Down | -0.2162931219 |
| GSE9593 | Down | -0.2489671860 |
| GSE43922 | Down | -0.6483711354 |
| GSE24585 | Down | -0.3595260001 |
| GSE37065 | Down | -0.0490509755 |
| GSE28863_A1 | Up | 0.1562411641 |
| GSE28863_A2 | Up | 0.0408712668 |
| GSE28863_A3 | Up | 0.0211131805 |
| GSE28863_A4 | Up | 0.2147975800 |
| GSE48662 | Down | -0.7259219657 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT001830 | Microarray//qRT-PCR//qRT-PCR;Other | Functional MTI (Weak) | 16549876 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049822 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
