HCSGD entry for TNFRSF10C
1. General information
| Official gene symbol | TNFRSF10C |
|---|---|
| Entrez ID | 8794 |
| Gene full name | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
| Other gene symbols | CD263 DCR1 DCR1-TNFR LIT TRAIL-R3 TRAILR3 TRID |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004888 | Transmembrane signaling receptor activity | TAS | molecular_function |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0031225 | Anchored component of membrane | IEA | cellular_component |
| GO:0045569 | TRAIL binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0497472930 | 0.9476482049 | 0.4889464152 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2069627151 |
| GSE13712_SHEAR | Up | 0.6499853102 |
| GSE13712_STATIC | Up | 0.3482059914 |
| GSE19018 | Up | 0.1699357073 |
| GSE19899_A1 | Up | 0.0324696848 |
| GSE19899_A2 | Up | 0.5585414257 |
| PubMed_21979375_A1 | Up | 0.1782328166 |
| PubMed_21979375_A2 | Up | 0.3082757757 |
| GSE35957 | Up | 0.0972072861 |
| GSE36640 | Up | 1.2965886166 |
| GSE54402 | Down | -0.4305876387 |
| GSE9593 | Down | -0.0488009491 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Down | -0.3218534362 |
| GSE28863_A2 | Up | 0.0806371072 |
| GSE28863_A3 | Down | -0.0329766088 |
| GSE28863_A4 | Up | 0.0611401680 |
| GSE48662 | Up | 0.9886710544 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 22258036 | Furthermore, DNA methylation levels of genes related to development of most or all tumor types, such as BRCA1, CCNA1, CDKN2A (p16), THBS1, TNFRSF10C and TNFRSF10D, were increased in BPA-exposed HMEC |
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