HCSGD entry for ADAM23
1. General information
| Official gene symbol | ADAM23 |
|---|---|
| Entrez ID | 8745 |
| Gene full name | ADAM metallopeptidase domain 23 |
| Other gene symbols | MDC-3 MDC3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004222 | Metalloendopeptidase activity | IEA | molecular_function |
| GO:0005178 | Integrin binding | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0007417 | Central nervous system development | TAS | biological_process |
| GO:0008237 | Metallopeptidase activity | TAS | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9082350481 | 0.0141932753 | 0.9999902473 | 0.2337804756 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0516529080 |
| GSE13712_SHEAR | Down | -0.5117468221 |
| GSE13712_STATIC | Down | -0.6637607894 |
| GSE19018 | Down | -0.2800962548 |
| GSE19899_A1 | Down | -0.0245037118 |
| GSE19899_A2 | Down | -0.3023609336 |
| PubMed_21979375_A1 | Down | -0.7365692075 |
| PubMed_21979375_A2 | Down | -0.3700708489 |
| GSE35957 | Up | 0.1277559729 |
| GSE36640 | Up | 2.2221789549 |
| GSE54402 | Down | -0.8307963577 |
| GSE9593 | Up | 0.0413137716 |
| GSE43922 | Up | 0.0081375231 |
| GSE24585 | Down | -0.4821699165 |
| GSE37065 | Up | 0.2094749832 |
| GSE28863_A1 | Down | -0.4094447107 |
| GSE28863_A2 | Down | -0.4530343580 |
| GSE28863_A3 | Down | -0.2106910141 |
| GSE28863_A4 | Down | -0.1825253094 |
| GSE48662 | Up | 0.0149596293 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
