HCSGD entry for TNFSF13
1. General information
| Official gene symbol | TNFSF13 |
|---|---|
| Entrez ID | 8741 |
| Gene full name | tumor necrosis factor (ligand) superfamily, member 13 |
| Other gene symbols | APRIL CD256 TALL-2 TALL2 TRDL-1 ZTNF2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002426 | Immunoglobulin production in mucosal tissue | IEA | biological_process |
| GO:0002636 | Positive regulation of germinal center formation | IEA | biological_process |
| GO:0005102 | Receptor binding | TAS | molecular_function |
| GO:0005125 | Cytokine activity | IEA | molecular_function |
| GO:0005164 | Tumor necrosis factor receptor binding | IEA | molecular_function |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006955 | Immune response | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0008284 | Positive regulation of cell proliferation | IEA | biological_process |
| GO:0009897 | External side of plasma membrane | IEA | cellular_component |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0016071 | MRNA metabolic process | TAS | biological_process |
| GO:0048298 | Positive regulation of isotype switching to IgA isotypes | IDA IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9037557198 | 0.4585305573 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0793463084 |
| GSE13712_SHEAR | Down | -0.1540450032 |
| GSE13712_STATIC | Down | -0.0809012165 |
| GSE19018 | Down | -0.1135888922 |
| GSE19899_A1 | Down | -0.0832368263 |
| GSE19899_A2 | Up | 0.1791930462 |
| PubMed_21979375_A1 | Up | 0.2498091381 |
| PubMed_21979375_A2 | Up | 0.0526056604 |
| GSE35957 | Up | 0.0608836460 |
| GSE36640 | Up | 0.0074743573 |
| GSE54402 | Down | -0.1317330257 |
| GSE9593 | Down | -0.1202977123 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Down | -0.2639498525 |
| GSE28863_A2 | Down | -0.3125051634 |
| GSE28863_A3 | Up | 0.1764589639 |
| GSE28863_A4 | Up | 0.0058941565 |
| GSE48662 | Up | 0.0990020066 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019711 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026351 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
