HCSGD entry for CBR3
1. General information
| Official gene symbol | CBR3 |
|---|---|
| Entrez ID | 874 |
| Gene full name | carbonyl reductase 3 |
| Other gene symbols | SDR21C2 hCBR3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000253 | 3-keto sterol reductase activity | IEA | molecular_function |
| GO:0004090 | Carbonyl reductase (NADPH) activity | IDA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0042376 | Phylloquinone catabolic process | IEA | biological_process |
| GO:0070402 | NADPH binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9835221648 | 0.0007485240 | 0.9999902473 | 0.0515289817 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.8873554103 |
| GSE13712_SHEAR | Down | -0.2327292278 |
| GSE13712_STATIC | Down | -0.1383187043 |
| GSE19018 | Up | 0.2272281925 |
| GSE19899_A1 | Down | -0.9317868810 |
| GSE19899_A2 | Down | -2.7089320299 |
| PubMed_21979375_A1 | Down | -3.7292186174 |
| PubMed_21979375_A2 | Down | -3.9052524890 |
| GSE35957 | Down | -0.8021673990 |
| GSE36640 | Down | -1.1573857976 |
| GSE54402 | Down | -0.5996637050 |
| GSE9593 | Up | 0.2280351655 |
| GSE43922 | Down | -0.0065398498 |
| GSE24585 | Up | 0.1111764987 |
| GSE37065 | Up | 0.1303747329 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.5644055854 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022826 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
