HCSGD entry for HRK
1. General information
| Official gene symbol | HRK |
|---|---|
| Entrez ID | 8739 |
| Gene full name | harakiri, BCL2 interacting protein (contains only BH3 domain) |
| Other gene symbols | DP5 HARAKIRI |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0032464 | Positive regulation of protein homooligomerization | IDA | biological_process |
| GO:0043065 | Positive regulation of apoptotic process | IMP | biological_process |
| GO:0090200 | Positive regulation of release of cytochrome c from mitochondria | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4618411421 | 0.8702766308 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1168631446 |
| GSE13712_SHEAR | Up | 0.0925666535 |
| GSE13712_STATIC | Up | 0.0861014724 |
| GSE19018 | Down | -0.0231923370 |
| GSE19899_A1 | Down | -0.0377912481 |
| GSE19899_A2 | Up | 0.2662644388 |
| PubMed_21979375_A1 | Up | 0.0728785496 |
| PubMed_21979375_A2 | Up | 0.0657784051 |
| GSE35957 | Up | 0.0198727202 |
| GSE36640 | Up | 0.0529453819 |
| GSE54402 | Up | 0.0022971892 |
| GSE9593 | Up | 0.0363015400 |
| GSE43922 | Up | 0.1329691230 |
| GSE24585 | Down | -0.0258663810 |
| GSE37065 | Up | 0.0616366304 |
| GSE28863_A1 | Down | -0.3254339432 |
| GSE28863_A2 | Down | -0.2262995710 |
| GSE28863_A3 | Up | 0.1780135367 |
| GSE28863_A4 | Up | 0.1340825924 |
| GSE48662 | Up | 0.4200746495 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
