HCSGD entry for GBF1
1. General information
| Official gene symbol | GBF1 |
|---|---|
| Entrez ID | 8729 |
| Gene full name | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| Other gene symbols | ARF1GEF |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | cellular_component |
| GO:0005086 | ARF guanyl-nucleotide exchange factor activity | IBA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005777 | Peroxisome | IEA | cellular_component |
| GO:0005788 | Endoplasmic reticulum lumen | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005795 | Golgi stack | IEA | cellular_component |
| GO:0005801 | Cis-Golgi network | IEA | cellular_component |
| GO:0005802 | Trans-Golgi network | IBA | cellular_component |
| GO:0006890 | Retrograde vesicle-mediated transport, Golgi to ER | TAS | biological_process |
| GO:0006892 | Post-Golgi vesicle-mediated transport | TAS | biological_process |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0016192 | Vesicle-mediated transport | IBA | biological_process |
| GO:0032012 | Regulation of ARF protein signal transduction | IEA | biological_process |
| GO:0043087 | Regulation of GTPase activity | IBA | biological_process |
| GO:0048205 | COPI coating of Golgi vesicle | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0107634512 | 0.8762819384 | 0.2631178869 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1033432951 |
| GSE13712_SHEAR | Up | 0.2749852411 |
| GSE13712_STATIC | Down | -0.1142001721 |
| GSE19018 | Up | 0.4014769138 |
| GSE19899_A1 | Down | -0.0465304081 |
| GSE19899_A2 | Up | 0.4738381560 |
| PubMed_21979375_A1 | Up | 0.6894012215 |
| PubMed_21979375_A2 | Up | 0.8633964891 |
| GSE35957 | Down | -0.3369370380 |
| GSE36640 | Up | 0.6504875712 |
| GSE54402 | Up | 0.3725966331 |
| GSE9593 | Down | -0.1260476788 |
| GSE43922 | Up | 0.0382820812 |
| GSE24585 | Up | 0.2991990383 |
| GSE37065 | Down | -0.1323814366 |
| GSE28863_A1 | Up | 0.9520260637 |
| GSE28863_A2 | Up | 0.9711747157 |
| GSE28863_A3 | Down | -0.3994068691 |
| GSE28863_A4 | Down | -0.0542730492 |
| GSE48662 | Up | 0.6562703789 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016484 | Proteomics | Functional MTI (Weak) | 21512034 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025834 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-let-7f-5p | MIMAT0000067 | MIRT051381 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052334 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052590 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
