HCSGD entry for TNFRSF25

1. General information

Official gene symbolTNFRSF25
Entrez ID8718
Gene full nametumor necrosis factor receptor superfamily, member 25
Other gene symbolsAPO-3 DDR3 DR3 LARD TNFRSF12 TR3 TRAMP WSL-1 WSL-LR
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004872Receptor activityNASmolecular_function
GO:0005031Tumor necrosis factor-activated receptor activityTASmolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0005829CytosolNAScellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006915Apoptotic processNASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007166Cell surface receptor signaling pathwayTASbiological_process
GO:0033209Tumor necrosis factor-mediated signaling pathwayTASbiological_process
GO:0042981Regulation of apoptotic processNASbiological_process
GO:0097190Apoptotic signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.20492056150.93088893660.87278243001.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1822961416
GSE13712_SHEARUp0.2831199186
GSE13712_STATICUp0.2754340283
GSE19018Up0.0661393037
GSE19899_A1Up0.1398153358
GSE19899_A2Up0.5088614683
PubMed_21979375_A1Up0.0659671325
PubMed_21979375_A2Up0.1995467247
GSE35957Down-0.0641173132
GSE36640Up0.0957094905
GSE54402Up0.2323645110
GSE9593Down-0.0638981520
GSE43922Up0.1177594747
GSE24585Down-0.0587502421
GSE37065Down-0.0478208203
GSE28863_A1Down-0.2712633996
GSE28863_A2Down-0.0639299663
GSE28863_A3Up0.3227998748
GSE28863_A4Down-0.0164155969
GSE48662Down-0.0277581664

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022463MicroarrayFunctional MTI (Weak)18668037
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.