HCSGD entry for EIF3J
1. General information
| Official gene symbol | EIF3J |
|---|---|
| Entrez ID | 8669 |
| Gene full name | eukaryotic translation initiation factor 3, subunit J |
| Other gene symbols | EIF3S1 eIF3-alpha eIF3-p35 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001731 | Formation of translation preinitiation complex | IEA | biological_process |
| GO:0003743 | Translation initiation factor activity | IC IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005852 | Eukaryotic translation initiation factor 3 complex | IDA IEA | cellular_component |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0006413 | Translational initiation | IC TAS | biological_process |
| GO:0006446 | Regulation of translational initiation | IEA | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016282 | Eukaryotic 43S preinitiation complex | IEA | cellular_component |
| GO:0033290 | Eukaryotic 48S preinitiation complex | IEA | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1288531363 | 0.5357078227 | 0.7290506019 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0523883551 |
| GSE13712_SHEAR | Up | 0.2547219277 |
| GSE13712_STATIC | Up | 0.2305612167 |
| GSE19018 | Down | -1.1053000981 |
| GSE19899_A1 | Up | 0.4390386829 |
| GSE19899_A2 | Up | 0.4005937704 |
| PubMed_21979375_A1 | Up | 0.4952314710 |
| PubMed_21979375_A2 | Up | 0.1997541025 |
| GSE35957 | Up | 0.1415249632 |
| GSE36640 | Up | 0.1095527634 |
| GSE54402 | Up | 0.3060894731 |
| GSE9593 | Down | -0.2426266972 |
| GSE43922 | Up | 0.2902225887 |
| GSE24585 | Down | -0.3367974557 |
| GSE37065 | Down | -0.1682679437 |
| GSE28863_A1 | Up | 0.2122136079 |
| GSE28863_A2 | Up | 0.1411440294 |
| GSE28863_A3 | Down | -0.1275082346 |
| GSE28863_A4 | Up | 0.0136727968 |
| GSE48662 | Down | -0.1900381982 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7e-5p | MIMAT0000066 | MIRT003932 | Luciferase reporter assay//Reporter assay | Non-Functional MTI | 15131085 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020659 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027570 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-320a | MIMAT0000510 | MIRT044772 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-let-7a-5p | MIMAT0000062 | NA | hsa-let-7a | 19939273 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
