HCSGD entry for EIF3H


1. General information

Official gene symbolEIF3H
Entrez ID8667
Gene full nameeukaryotic translation initiation factor 3, subunit H
Other gene symbolsEIF3S3 eIF3-gamma eIF3-p40
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001731Formation of translation preinitiation complexIEAbiological_process
GO:0003743Translation initiation factor activityIC IDA IEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005852Eukaryotic translation initiation factor 3 complexIDA IEAcellular_component
GO:0006412TranslationTASbiological_process
GO:0006413Translational initiationIC IDA TASbiological_process
GO:0006446Regulation of translational initiationTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016282Eukaryotic 43S preinitiation complexIEAcellular_component
GO:0033290Eukaryotic 48S preinitiation complexIEAcellular_component
GO:0044267Cellular protein metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.96889038790.04847197290.99999024730.4119569906

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2811653231
GSE13712_SHEARDown-0.5632852853
GSE13712_STATICDown-0.1806073616
GSE19018Down-0.3944192368
GSE19899_A1Down-0.0496283937
GSE19899_A2Down-0.4947601997
PubMed_21979375_A1Up0.0976849465
PubMed_21979375_A2Down-0.9997129552
GSE35957Down-0.1510715733
GSE36640Down-0.2032009130
GSE54402Down-0.3257967001
GSE9593Up0.0822745433
GSE43922Up0.0624961214
GSE24585Up0.0610471703
GSE37065Down-0.2340873995
GSE28863_A1Up0.2493428435
GSE28863_A2Down-0.0949344838
GSE28863_A3Down-0.2070050614
GSE28863_A4Up0.0765129927
GSE48662Down-0.1767935455

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-16-5pMIMAT0000069MIRT031946ProteomicsFunctional MTI (Weak)18668040
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.