HCSGD entry for SLC25A12
1. General information
| Official gene symbol | SLC25A12 |
|---|---|
| Entrez ID | 8604 |
| Gene full name | solute carrier family 25 (aspartate/glutamate carrier), member 12 |
| Other gene symbols | AGC1 ARALAR |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003333 | Amino acid transmembrane transport | IDA | biological_process |
| GO:0005313 | L-glutamate transmembrane transporter activity | IDA | molecular_function |
| GO:0005509 | Calcium ion binding | IDA IEA | molecular_function |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | TAS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0006006 | Glucose metabolic process | TAS | biological_process |
| GO:0006094 | Gluconeogenesis | TAS | biological_process |
| GO:0015183 | L-aspartate transmembrane transporter activity | IDA | molecular_function |
| GO:0015810 | Aspartate transport | IDA | biological_process |
| GO:0015813 | L-glutamate transport | IDA | biological_process |
| GO:0016021 | Integral component of membrane | IEA NAS | cellular_component |
| GO:0034220 | Ion transmembrane transport | IDA | biological_process |
| GO:0043490 | Malate-aspartate shuttle | IDA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0051592 | Response to calcium ion | IDA | biological_process |
| GO:0055085 | Transmembrane transport | IEA | biological_process |
| GO:1902475 | L-alpha-amino acid transmembrane transport | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0364204969 | 0.6085349113 | 0.4332829125 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.6566724023 |
| GSE13712_SHEAR | Up | 0.0179983124 |
| GSE13712_STATIC | Up | 0.3704694890 |
| GSE19018 | Down | -0.0925480187 |
| GSE19899_A1 | Up | 0.1869882882 |
| GSE19899_A2 | Up | 0.6328430296 |
| PubMed_21979375_A1 | Up | 0.6964644950 |
| PubMed_21979375_A2 | Up | 1.2387176889 |
| GSE35957 | Down | -0.1241218483 |
| GSE36640 | Up | 0.3883433073 |
| GSE54402 | Down | -0.1990523841 |
| GSE9593 | Down | -0.2494891438 |
| GSE43922 | Up | 0.0011292152 |
| GSE24585 | Up | 0.3206752885 |
| GSE37065 | Up | 0.1954529723 |
| GSE28863_A1 | Up | 0.0857236099 |
| GSE28863_A2 | Up | 0.5950881968 |
| GSE28863_A3 | Down | -1.0226554419 |
| GSE28863_A4 | Down | -0.2191421933 |
| GSE48662 | Up | 0.0622838728 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Aspartic Acid | DB00128 | NUTR00016 | EXPT01823 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT032465 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-766-3p | MIMAT0003888 | MIRT039054 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047856 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7f-5p | MIMAT0000067 | MIRT051393 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
