HCSGD entry for CAV2
1. General information
| Official gene symbol | CAV2 |
|---|---|
| Entrez ID | 858 |
| Gene full name | caveolin 2 |
| Other gene symbols | CAV |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0001937 | Negative regulation of endothelial cell proliferation | IEA ISS | biological_process |
| GO:0001938 | Positive regulation of endothelial cell proliferation | IEA | biological_process |
| GO:0002080 | Acrosomal membrane | IEA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | IDA | cellular_component |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | ISS | cellular_component |
| GO:0005811 | Lipid particle | IEA | cellular_component |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0005887 | Integral component of plasma membrane | IDA | cellular_component |
| GO:0005901 | Caveola | IDA IEA | cellular_component |
| GO:0006906 | Vesicle fusion | IDA | biological_process |
| GO:0007005 | Mitochondrion organization | IEA ISS | biological_process |
| GO:0007029 | Endoplasmic reticulum organization | IEA ISS | biological_process |
| GO:0007088 | Regulation of mitosis | IEP | biological_process |
| GO:0007268 | Synaptic transmission | IEA | biological_process |
| GO:0009986 | Cell surface | IEA | cellular_component |
| GO:0016020 | Membrane | IDA | cellular_component |
| GO:0016050 | Vesicle organization | IDA | biological_process |
| GO:0019905 | Syntaxin binding | IEA | molecular_function |
| GO:0030133 | Transport vesicle | IDA | cellular_component |
| GO:0030512 | Negative regulation of transforming growth factor beta receptor signaling pathway | IEA | biological_process |
| GO:0031234 | Extrinsic component of cytoplasmic side of plasma membrane | IDA | cellular_component |
| GO:0031410 | Cytoplasmic vesicle | IDA | cellular_component |
| GO:0031748 | D1 dopamine receptor binding | IPI | molecular_function |
| GO:0042803 | Protein homodimerization activity | IDA | molecular_function |
| GO:0043234 | Protein complex | IEA | cellular_component |
| GO:0045121 | Membrane raft | IDA | cellular_component |
| GO:0048278 | Vesicle docking | IDA | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IDA | cellular_component |
| GO:0048741 | Skeletal muscle fiber development | IEA ISS | biological_process |
| GO:0051219 | Phosphoprotein binding | IEA | molecular_function |
| GO:0051259 | Protein oligomerization | IEA | biological_process |
| GO:0060161 | Positive regulation of dopamine receptor signaling pathway | IMP | biological_process |
| GO:0070836 | Caveola assembly | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7355749820 | 0.0131691881 | 0.9999902473 | 0.2258842448 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2618582736 |
| GSE13712_SHEAR | Down | -0.1339723803 |
| GSE13712_STATIC | Down | -0.1736953238 |
| GSE19018 | Up | 0.6911564403 |
| GSE19899_A1 | Down | -0.5756495469 |
| GSE19899_A2 | Down | -1.0588611687 |
| PubMed_21979375_A1 | Down | -1.7032363952 |
| PubMed_21979375_A2 | Down | -1.1428796830 |
| GSE35957 | Up | 0.3143948747 |
| GSE36640 | Up | 1.3167685541 |
| GSE54402 | Down | -1.4908825659 |
| GSE9593 | Up | 0.1271699057 |
| GSE43922 | Down | -0.4930566628 |
| GSE24585 | Up | 0.0175685460 |
| GSE37065 | Down | -0.1419877104 |
| GSE28863_A1 | Down | -0.2943729943 |
| GSE28863_A2 | Down | -0.0638839521 |
| GSE28863_A3 | Up | 0.1780310683 |
| GSE28863_A4 | Down | -0.0035495822 |
| GSE48662 | Down | -0.2733419108 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-199a-3p | MIMAT0000232 | MIRT006655 | Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 21807947 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT028136 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029751 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord

