HCSGD entry for STK16


1. General information

Official gene symbolSTK16
Entrez ID8576
Gene full nameserine/threonine kinase 16
Other gene symbolsKRCT MPSK PKL12 TSF1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptionIEAmolecular_function
GO:0004672Protein kinase activityIEAmolecular_function
GO:0004674Protein serine/threonine kinase activityIEAmolecular_function
GO:0004715Non-membrane spanning protein tyrosine kinase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005798Golgi-associated vesicleIEAcellular_component
GO:0016020MembraneIEAcellular_component
GO:0046777Protein autophosphorylationIDAbiological_process
GO:0048471Perinuclear region of cytoplasmIEAcellular_component
GO:0071560Cellular response to transforming growth factor beta stimulusIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.46773450860.64990569510.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1429865042
GSE13712_SHEARDown-0.3336598635
GSE13712_STATICDown-0.1517731396
GSE19018Up0.2854773692
GSE19899_A1Up0.0604204337
GSE19899_A2Down-0.0691178726
PubMed_21979375_A1Down-0.0261779607
PubMed_21979375_A2Down-0.2659274703
GSE35957Up0.0611113276
GSE36640Up0.2154611801
GSE54402Up0.0121457452
GSE9593Up0.0363768709
GSE43922Down-0.0800190857
GSE24585Down-0.0344065468
GSE37065Up0.0328678421
GSE28863_A1Up0.0875812429
GSE28863_A2Up0.0702874216
GSE28863_A3Up0.0027734840
GSE28863_A4Down-0.1367448083
GSE48662Up0.6890419626

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029140MicroarrayFunctional MTI (Weak)19088304
hsa-miR-744-5pMIMAT0004945MIRT037413CLASHFunctional MTI (Weak)23622248
hsa-miR-324-3pMIMAT0000762MIRT042840CLASHFunctional MTI (Weak)23622248
hsa-miR-365a-3pMIMAT0000710MIRT044034CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.