HCSGD entry for AKR7A2
1. General information
| Official gene symbol | AKR7A2 |
|---|---|
| Entrez ID | 8574 |
| Gene full name | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) |
| Other gene symbols | AFAR AFAR1 AFB1-AR1 AKR7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004032 | Alditol:NADP+ 1-oxidoreductase activity | TAS | molecular_function |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0006081 | Cellular aldehyde metabolic process | TAS | biological_process |
| GO:0009055 | Electron carrier activity | TAS | molecular_function |
| GO:0019119 | Phenanthrene-9,10-epoxide hydrolase activity | IDA | molecular_function |
| GO:0044597 | Daunorubicin metabolic process | IMP | biological_process |
| GO:0044598 | Doxorubicin metabolic process | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9618829300 | 0.0279388017 | 0.9999902473 | 0.3179322093 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3382435198 |
| GSE13712_SHEAR | Down | -0.3853279120 |
| GSE13712_STATIC | Down | -0.4081024841 |
| GSE19018 | Up | 0.6324899022 |
| GSE19899_A1 | Down | -0.2883965611 |
| GSE19899_A2 | Up | 0.1384365281 |
| PubMed_21979375_A1 | Up | 0.4966397457 |
| PubMed_21979375_A2 | Down | -0.7574591889 |
| GSE35957 | Down | -0.3250958701 |
| GSE36640 | Down | -0.2147575929 |
| GSE54402 | Up | 0.0975095700 |
| GSE9593 | Down | -0.2269497815 |
| GSE43922 | Down | -0.1991155787 |
| GSE24585 | Down | -0.0392536401 |
| GSE37065 | Down | -0.1993301673 |
| GSE28863_A1 | Down | -0.2290213216 |
| GSE28863_A2 | Down | -0.1131820178 |
| GSE28863_A3 | Down | -0.0367133066 |
| GSE28863_A4 | Down | -0.3715310190 |
| GSE48662 | Down | -0.2452121319 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020602 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025267 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025659 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050598 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
