HCSGD entry for KMO
1. General information
| Official gene symbol | KMO |
|---|---|
| Entrez ID | 8564 |
| Gene full name | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| Other gene symbols | dJ317G22.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004502 | Kynurenine 3-monooxygenase activity | IDA | molecular_function |
| GO:0005741 | Mitochondrial outer membrane | ISS | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006569 | Tryptophan catabolic process | TAS | biological_process |
| GO:0009435 | NAD biosynthetic process | IEA | biological_process |
| GO:0009651 | Response to salt stress | IDA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016174 | NAD(P)H oxidase activity | IDA | molecular_function |
| GO:0019441 | Tryptophan catabolic process to kynurenine | IEA | biological_process |
| GO:0019805 | Quinolinate biosynthetic process | IEA | biological_process |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0050660 | Flavin adenine dinucleotide binding | IDA | molecular_function |
| GO:0070189 | Kynurenine metabolic process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5541127275 | 0.8955003229 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1321817318 |
| GSE13712_SHEAR | Down | -0.1015283514 |
| GSE13712_STATIC | Down | -0.0941203843 |
| GSE19018 | Up | 0.1478398636 |
| GSE19899_A1 | Up | 0.2131884490 |
| GSE19899_A2 | Up | 0.1161231022 |
| PubMed_21979375_A1 | Down | -0.0064413985 |
| PubMed_21979375_A2 | Down | -0.1146436457 |
| GSE35957 | Up | 0.0952749731 |
| GSE36640 | Up | 0.1850157144 |
| GSE54402 | Up | 0.0004356992 |
| GSE9593 | Up | 0.1229422364 |
| GSE43922 | Up | 0.0197686205 |
| GSE24585 | Down | -0.0751228815 |
| GSE37065 | Up | 0.3848609480 |
| GSE28863_A1 | Down | -0.1124010317 |
| GSE28863_A2 | Up | 0.0414643332 |
| GSE28863_A3 | Up | 0.1006918907 |
| GSE28863_A4 | Up | 0.0144152937 |
| GSE48662 | Up | 0.0051146945 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
