HCSGD entry for SCIN

1. General information

Official gene symbolSCIN
Entrez ID85477
Gene full namescinderin
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001786Phosphatidylserine bindingISSmolecular_function
GO:0003779Actin bindingIEA ISS TASmolecular_function
GO:0005509Calcium ion bindingISS TASmolecular_function
GO:00055451-phosphatidylinositol bindingTASmolecular_function
GO:0005546Phosphatidylinositol-4,5-bisphosphate bindingISSmolecular_function
GO:0005737CytoplasmIDA ISScellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0005938Cell cortexISScellular_component
GO:0008285Negative regulation of cell proliferationIMPbiological_process
GO:0017156Calcium ion-dependent exocytosisISSbiological_process
GO:0032330Regulation of chondrocyte differentiationISSbiological_process
GO:0043065Positive regulation of apoptotic processIMPbiological_process
GO:0043234Protein complexIEAcellular_component
GO:0045010Actin nucleationISSbiological_process
GO:0045654Positive regulation of megakaryocyte differentiationIMPbiological_process
GO:0051014Actin filament severingIMPbiological_process
GO:0051015Actin filament bindingISSmolecular_function
GO:0051047Positive regulation of secretionISSbiological_process
GO:0051693Actin filament cappingIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.54530406520.01178460920.99999024730.2145214483

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1416731011
GSE13712_SHEARDown-0.0829631221
GSE13712_STATICDown-0.0246629311
GSE19018Up0.0666383091
GSE19899_A1Down-0.0273973460
GSE19899_A2Down-0.0069126657
PubMed_21979375_A1Down-0.0428358187
PubMed_21979375_A2Up0.0847714201
GSE35957Up2.9131362159
GSE36640Down-0.0814363465
GSE54402Down-0.0053084470
GSE9593Up0.0939196615
GSE43922Up0.0136828369
GSE24585Down-0.5552958296
GSE37065Up0.0694125782
GSE28863_A1Down-1.5919799099
GSE28863_A2Down-0.0340271967
GSE28863_A3Down-3.0614761350
GSE28863_A4Down-0.1058103349
GSE48662Down-0.2557813721

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017918MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.