HCSGD entry for SSH2
1. General information
| Official gene symbol | SSH2 |
|---|---|
| Entrez ID | 85464 |
| Gene full name | slingshot protein phosphatase 2 |
| Other gene symbols | SSH-2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003779 | Actin binding | IDA | molecular_function |
| GO:0004721 | Phosphoprotein phosphatase activity | IDA | molecular_function |
| GO:0004725 | Protein tyrosine phosphatase activity | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IBA | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0006470 | Protein dephosphorylation | IMP | biological_process |
| GO:0008064 | Regulation of actin polymerization or depolymerization | IBA | biological_process |
| GO:0008138 | Protein tyrosine/serine/threonine phosphatase activity | IBA IEA | molecular_function |
| GO:0010591 | Regulation of lamellipodium assembly | IBA | biological_process |
| GO:0030036 | Actin cytoskeleton organization | IMP | biological_process |
| GO:0050770 | Regulation of axonogenesis | IBA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0552707762 | 0.9459468029 | 0.5117883222 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0188873237 |
| GSE13712_SHEAR | Down | -0.1889006551 |
| GSE13712_STATIC | Down | -0.0646318471 |
| GSE19018 | Up | 0.1533557799 |
| GSE19899_A1 | Up | 0.1380287281 |
| GSE19899_A2 | Up | 0.3646676999 |
| PubMed_21979375_A1 | Up | 0.2864264336 |
| PubMed_21979375_A2 | Up | 0.6317808970 |
| GSE35957 | Down | -0.0613103222 |
| GSE36640 | Up | 0.4818193239 |
| GSE54402 | Down | -0.0506952536 |
| GSE9593 | Down | -0.0022497139 |
| GSE43922 | Up | 0.3363130354 |
| GSE24585 | Up | 0.2065575902 |
| GSE37065 | Up | 0.2180326400 |
| GSE28863_A1 | Up | 0.8335932028 |
| GSE28863_A2 | Up | 0.7012897157 |
| GSE28863_A3 | Down | -0.6027683602 |
| GSE28863_A4 | Up | 0.0007618641 |
| GSE48662 | Down | -0.1381933731 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030263 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-130b-5p | MIMAT0004680 | MIRT038300 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046800 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
