HCSGD entry for HELZ2
1. General information
| Official gene symbol | HELZ2 |
|---|---|
| Entrez ID | 85441 |
| Gene full name | helicase with zinc finger 2, transcriptional coactivator |
| Other gene symbols | PDIP-1 PRIC285 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0004386 | Helicase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0030374 | Ligand-dependent nuclear receptor transcription coactivator activity | IDA | molecular_function |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0399549409 | 0.9552850348 | 0.4486578498 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0435651999 |
| GSE13712_SHEAR | Up | 1.6042465860 |
| GSE13712_STATIC | Up | 1.0631686056 |
| GSE19018 | Up | 0.0842873634 |
| GSE19899_A1 | Down | -0.0764284163 |
| GSE19899_A2 | Up | 0.1018716363 |
| PubMed_21979375_A1 | Down | -0.0692285107 |
| PubMed_21979375_A2 | Up | 0.0161972213 |
| GSE35957 | Down | -0.5454697285 |
| GSE36640 | Up | 0.1118559656 |
| GSE54402 | Up | 0.0832708968 |
| GSE9593 | Down | -0.0678153964 |
| GSE43922 | Up | 0.0498564018 |
| GSE24585 | Up | 0.7268349268 |
| GSE37065 | Up | 0.3961146770 |
| GSE28863_A1 | Up | 0.0891885712 |
| GSE28863_A2 | Up | 0.4996433523 |
| GSE28863_A3 | Up | 0.3387044117 |
| GSE28863_A4 | Up | 0.0819674003 |
| GSE48662 | Up | 0.1303887007 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
