HCSGD entry for NKD2

1. General information

Official gene symbolNKD2
Entrez ID85409
Gene full namenaked cuticle homolog 2 (Drosophila)
Other gene symbolsNaked2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0006887ExocytosisIEAbiological_process
GO:0010954Positive regulation of protein processingIDAbiological_process
GO:0016023Cytoplasmic membrane-bounded vesicleIEAcellular_component
GO:0016055Wnt signaling pathwayIEAbiological_process
GO:0016323Basolateral plasma membraneIDAcellular_component
GO:0016328Lateral plasma membraneIDAcellular_component
GO:0019838Growth factor bindingIPImolecular_function
GO:0031410Cytoplasmic vesicleIDAcellular_component
GO:0031625Ubiquitin protein ligase bindingIPImolecular_function
GO:0032436Positive regulation of proteasomal ubiquitin-dependent protein catabolic processIMPbiological_process
GO:0048210Golgi vesicle fusion to target membraneIMPbiological_process
GO:0071944Cell peripheryIDAcellular_component
GO:0072661Protein targeting to plasma membraneIMPbiological_process
GO:0090004Positive regulation of establishment of protein localization to plasma membraneIDAbiological_process
GO:0090090Negative regulation of canonical Wnt signaling pathwayIDA IMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.49600155770.77473598650.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1552815051
GSE13712_SHEARDown-0.1257954137
GSE13712_STATICDown-0.0798429047
GSE19018Up0.0390031613
GSE19899_A1Up0.1655471985
GSE19899_A2Up0.4377361596
PubMed_21979375_A1Down-0.0623552494
PubMed_21979375_A2Down-0.0784975707
GSE35957Down-0.5978435692
GSE36640Up0.1440073476
GSE54402Down-0.0710244145
GSE9593Up0.0330012118
GSE43922Up0.1129003223
GSE24585Down-0.0514928320
GSE37065Down-0.1173598878
GSE28863_A1Down-0.0034102100
GSE28863_A2Up0.1372533721
GSE28863_A3Up0.2896079237
GSE28863_A4Up0.1267406659
GSE48662Down-0.1378325495

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.