HCSGD entry for IFITM1
1. General information
| Official gene symbol | IFITM1 |
|---|---|
| Entrez ID | 8519 |
| Gene full name | interferon induced transmembrane protein 1 |
| Other gene symbols | 9-27 CD225 DSPA2a IFI17 LEU13 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001503 | Ossification | IEA | biological_process |
| GO:0005057 | Receptor signaling protein activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0007166 | Cell surface receptor signaling pathway | TAS | biological_process |
| GO:0008285 | Negative regulation of cell proliferation | IMP | biological_process |
| GO:0009615 | Response to virus | IDA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019221 | Cytokine-mediated signaling pathway | TAS | biological_process |
| GO:0030336 | Negative regulation of cell migration | IMP | biological_process |
| GO:0034341 | Response to interferon-gamma | IDA | biological_process |
| GO:0035455 | Response to interferon-alpha | IDA | biological_process |
| GO:0035456 | Response to interferon-beta | IDA | biological_process |
| GO:0035556 | Intracellular signal transduction | TAS | biological_process |
| GO:0045071 | Negative regulation of viral genome replication | IDA IMP | biological_process |
| GO:0045669 | Positive regulation of osteoblast differentiation | IMP | biological_process |
| GO:0046597 | Negative regulation of viral entry into host cell | IDA | biological_process |
| GO:0050776 | Regulation of immune response | TAS | biological_process |
| GO:0051607 | Defense response to virus | IEA | biological_process |
| GO:0060337 | Type I interferon signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0028310247 | 0.0026461609 | 0.1422049618 | 0.1024196193 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.8078321841 |
| GSE13712_SHEAR | Up | 5.6274175584 |
| GSE13712_STATIC | Up | 4.1378731376 |
| GSE19018 | Down | -1.2193830294 |
| GSE19899_A1 | Down | -2.2988604291 |
| GSE19899_A2 | Down | -1.9239816722 |
| PubMed_21979375_A1 | Down | -2.0220149739 |
| PubMed_21979375_A2 | Down | -2.7972814117 |
| GSE35957 | Down | -1.6846794794 |
| GSE36640 | Up | 1.9986462859 |
| GSE54402 | Down | -2.4848266740 |
| GSE9593 | Down | -0.9068948671 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Up | 1.3421535429 |
| GSE28863_A2 | Up | 1.7950198635 |
| GSE28863_A3 | Up | 0.0500861154 |
| GSE28863_A4 | Down | -0.0778599382 |
| GSE48662 | Up | 0.4871497842 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-130a-3p | MIMAT0000425 | MIRT006992 | Luciferase reporter assay | Functional MTI | 22787204 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT018732 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-146a-5p | MIMAT0000449 | MIRT021233 | Microarray | Functional MTI (Weak) | 18057241 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
