HCSGD entry for USP45
1. General information
| Official gene symbol | USP45 |
|---|---|
| Entrez ID | 85015 |
| Gene full name | ubiquitin specific peptidase 45 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004221 | Ubiquitin thiolesterase activity | IEA | molecular_function |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | IEA | biological_process |
| GO:0008234 | Cysteine-type peptidase activity | IEA | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2037489799 | 0.3850719350 | 0.8707382530 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1032527517 |
| GSE13712_SHEAR | Up | 0.2913072389 |
| GSE13712_STATIC | Up | 0.5388154169 |
| GSE19018 | Down | -0.3482467313 |
| GSE19899_A1 | Up | 0.5073836038 |
| GSE19899_A2 | Up | 0.5145258811 |
| PubMed_21979375_A1 | Up | 1.0470459408 |
| PubMed_21979375_A2 | Up | 0.1496524968 |
| GSE35957 | Down | -0.4147411771 |
| GSE36640 | Down | -0.3069011630 |
| GSE54402 | Up | 0.0950270183 |
| GSE9593 | Down | -0.5304472146 |
| GSE43922 | Up | 0.2553911895 |
| GSE24585 | Up | 0.0707047776 |
| GSE37065 | Down | -0.1108802504 |
| GSE28863_A1 | Down | -0.0090111178 |
| GSE28863_A2 | Up | 0.0812355814 |
| GSE28863_A3 | Down | -0.4393623005 |
| GSE28863_A4 | Down | -0.0293935400 |
| GSE48662 | Down | -0.3710684233 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-192-5p | MIMAT0000222 | MIRT026646 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-32-5p | MIMAT0000090 | MIRT028362 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-let-7f-5p | MIMAT0000067 | MIRT051365 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
