HCSGD entry for TNS4


1. General information

Official gene symbolTNS4
Entrez ID84951
Gene full nametensin 4
Other gene symbolsCTEN
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003779Actin bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0005925Focal adhesionIDAcellular_component
GO:0006915Apoptotic processIEAbiological_process
GO:0008104Protein localizationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.60450014820.75220551270.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0202498384
GSE13712_SHEARUp0.1329924733
GSE13712_STATICDown-0.1441073548
GSE19018Down-0.0801244759
GSE19899_A1Up0.1284009101
GSE19899_A2Up0.1920648927
PubMed_21979375_A1Down-0.1513411578
PubMed_21979375_A2Up0.0165334682
GSE35957Down-0.0378761033
GSE36640Down-0.1746177180
GSE54402Down-0.0009858669
GSE9593Down-0.0202587651
GSE43922Up0.0748381201
GSE24585Up0.1286914273
GSE37065Up0.2549848542
GSE28863_A1Down-0.2482970959
GSE28863_A2Down-0.1234026297
GSE28863_A3Up0.2718415345
GSE28863_A4Up0.0591940938
GSE48662Up0.1555556905

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT003769MicroarrayFunctional MTI (Weak)15685193
hsa-miR-335-5pMIMAT0000765MIRT018760MicroarrayFunctional MTI (Weak)18185580
hsa-miR-124-3pMIMAT0000422MIRT023010MicroarrayFunctional MTI (Weak)18668037
hsa-miR-26b-5pMIMAT0000083MIRT030073MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-1MIMAT0000416NAhsa-miR-115685193
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.