HCSGD entry for PRSS12
1. General information
| Official gene symbol | PRSS12 |
|---|---|
| Entrez ID | 8492 |
| Gene full name | protease, serine, 12 (neurotrypsin, motopsin) |
| Other gene symbols | BSSP-3 BSSP3 MRT1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004252 | Serine-type endopeptidase activity | IEA | molecular_function |
| GO:0005044 | Scavenger receptor activity | IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005886 | Plasma membrane | ISS | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0006887 | Exocytosis | ISS | biological_process |
| GO:0008236 | Serine-type peptidase activity | TAS | molecular_function |
| GO:0030424 | Axon | ISS | cellular_component |
| GO:0030425 | Dendrite | IEA | cellular_component |
| GO:0031410 | Cytoplasmic vesicle | IEA | cellular_component |
| GO:0031638 | Zymogen activation | IEA | biological_process |
| GO:0043083 | Synaptic cleft | IEA | cellular_component |
| GO:0043195 | Terminal bouton | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3301577106 | 0.0000427377 | 0.9999902473 | 0.0110578431 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.1485950593 |
| GSE13712_SHEAR | Up | 0.0164439650 |
| GSE13712_STATIC | Down | -0.0537421966 |
| GSE19018 | Down | -0.6567846178 |
| GSE19899_A1 | Down | -1.9636176757 |
| GSE19899_A2 | Down | -4.2845064517 |
| PubMed_21979375_A1 | Down | -4.4257874896 |
| PubMed_21979375_A2 | Down | -5.2160342386 |
| GSE35957 | Up | 2.5595612952 |
| GSE36640 | Down | -1.7572797388 |
| GSE54402 | Down | -3.8637783219 |
| GSE9593 | Up | 0.5013375569 |
| GSE43922 | Down | -2.7093689566 |
| GSE24585 | Down | -0.5239575237 |
| GSE37065 | Down | -0.2847171212 |
| GSE28863_A1 | Up | 0.6401831596 |
| GSE28863_A2 | Up | 1.1342195519 |
| GSE28863_A3 | Down | -0.9409858613 |
| GSE28863_A4 | Down | -0.1609193430 |
| GSE48662 | Up | 0.5053317056 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
