HCSGD entry for SLC7A3
1. General information
| Official gene symbol | SLC7A3 |
|---|---|
| Entrez ID | 84889 |
| Gene full name | solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 |
| Other gene symbols | ATRC3 CAT-3 CAT3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006811 | Ion transport | TAS | biological_process |
| GO:0006865 | Amino acid transport | TAS | biological_process |
| GO:0015181 | Arginine transmembrane transporter activity | IEA | molecular_function |
| GO:0015189 | L-lysine transmembrane transporter activity | IEA | molecular_function |
| GO:0015326 | Cationic amino acid transmembrane transporter activity | IEA | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8284792865 | 0.6823117701 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1155389243 |
| GSE13712_SHEAR | Down | -0.0925069791 |
| GSE13712_STATIC | Down | -0.0085890551 |
| GSE19018 | Up | 0.0277508724 |
| GSE19899_A1 | Up | 0.0896138610 |
| GSE19899_A2 | Up | 0.0887827407 |
| PubMed_21979375_A1 | Down | -0.2503234664 |
| PubMed_21979375_A2 | Down | -0.0868647770 |
| GSE35957 | Up | 0.0113556944 |
| GSE36640 | Down | -0.0027466839 |
| GSE54402 | Down | -0.0375906248 |
| GSE9593 | Down | -0.0264719920 |
| GSE43922 | Up | 0.1488470155 |
| GSE24585 | Down | -0.2323452424 |
| GSE37065 | Down | -0.1154318019 |
| GSE28863_A1 | Up | 0.0423614571 |
| GSE28863_A2 | Up | 0.0507675063 |
| GSE28863_A3 | Up | 0.2077390448 |
| GSE28863_A4 | Up | 0.0798658585 |
| GSE48662 | Up | 0.0545760439 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Lysine | DB00123 | NUTR00037 | DB11101 |
| L-Arginine | DB00125 | NUTR00014 |
| L-Ornithine | DB00129 | NUTR00043 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
