HCSGD entry for CDC42BPA
1. General information
| Official gene symbol | CDC42BPA |
|---|---|
| Entrez ID | 8476 |
| Gene full name | CDC42 binding protein kinase alpha (DMPK-like) |
| Other gene symbols | MRCK MRCKA PK428 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000226 | Microtubule cytoskeleton organization | IEA | biological_process |
| GO:0000287 | Magnesium ion binding | IDA | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IDA IEA | molecular_function |
| GO:0005083 | Small GTPase regulator activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IDA IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005911 | Cell-cell junction | ISS | cellular_component |
| GO:0006468 | Protein phosphorylation | IDA | biological_process |
| GO:0007097 | Nuclear migration | IEA | biological_process |
| GO:0016477 | Cell migration | IMP | biological_process |
| GO:0031032 | Actomyosin structure organization | IMP | biological_process |
| GO:0031252 | Cell leading edge | ISS | cellular_component |
| GO:0031532 | Actin cytoskeleton reorganization | IDA IEA | biological_process |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0042641 | Actomyosin | IDA | cellular_component |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2719560541 | 0.5720876676 | 0.9686272395 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1986915108 |
| GSE13712_SHEAR | Up | 0.0965100932 |
| GSE13712_STATIC | Down | -0.1090605247 |
| GSE19018 | Up | 0.0610257468 |
| GSE19899_A1 | Up | 0.0471734914 |
| GSE19899_A2 | Down | -0.0178971640 |
| PubMed_21979375_A1 | Down | -0.1435197517 |
| PubMed_21979375_A2 | Up | 0.3901458599 |
| GSE35957 | Down | -0.0596212824 |
| GSE36640 | Down | -0.0096450937 |
| GSE54402 | Up | 0.0123513387 |
| GSE9593 | Up | 0.2223431588 |
| GSE43922 | Down | -0.0150486197 |
| GSE24585 | Up | 0.1993937924 |
| GSE37065 | Down | -0.1582998315 |
| GSE28863_A1 | Up | 0.7852938127 |
| GSE28863_A2 | Up | 0.8465046177 |
| GSE28863_A3 | Down | -0.1826048702 |
| GSE28863_A4 | Down | -0.2408355317 |
| GSE48662 | Down | -0.0587158691 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017761 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT048711 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051756 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
