HCSGD entry for PLEKHA8
1. General information
| Official gene symbol | PLEKHA8 |
|---|---|
| Entrez ID | 84725 |
| Gene full name | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 |
| Other gene symbols | FAPP2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0005802 | Trans-Golgi network | IDA | cellular_component |
| GO:0006869 | Lipid transport | IDA | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0017089 | Glycolipid transporter activity | IDA IEA | molecular_function |
| GO:0035621 | ER to Golgi ceramide transport | IDA | biological_process |
| GO:0051861 | Glycolipid binding | IDA IEA | molecular_function |
| GO:0070273 | Phosphatidylinositol-4-phosphate binding | IDA | molecular_function |
| GO:0097001 | Ceramide binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5485691615 | 0.6689122146 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0738648947 |
| GSE13712_SHEAR | Up | 0.0152389842 |
| GSE13712_STATIC | Up | 0.1171550990 |
| GSE19018 | Down | -0.0009894328 |
| GSE19899_A1 | Down | -0.0853061212 |
| GSE19899_A2 | Down | -0.1796649380 |
| PubMed_21979375_A1 | Up | 0.2645652879 |
| PubMed_21979375_A2 | Down | -0.0070887039 |
| GSE35957 | Down | -0.0454157826 |
| GSE36640 | Down | -0.3408874756 |
| GSE54402 | Up | 0.1672375878 |
| GSE9593 | Down | -0.0750560052 |
| GSE43922 | Up | 0.0380802823 |
| GSE24585 | Down | -0.2709670705 |
| GSE37065 | Up | 0.1395708035 |
| GSE28863_A1 | Up | 0.4314142313 |
| GSE28863_A2 | Up | 0.5143562915 |
| GSE28863_A3 | Down | -0.1599649804 |
| GSE28863_A4 | Up | 0.1477445318 |
| GSE48662 | Down | -0.1504921993 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-125b-5p | MIMAT0000423 | MIRT004995 | Microarray | Functional MTI (Weak) | 17891175 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
