HCSGD entry for PPP1R9B

1. General information

Official gene symbolPPP1R9B
Entrez ID84687
Gene full nameprotein phosphatase 1, regulatory subunit 9B
Other gene symbolsPPP1R6 PPP1R9 SPINO Spn
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000164Protein phosphatase type 1 complexTAScellular_component
GO:0001560Regulation of cell growth by extracellular stimulusTASbiological_process
GO:0001932Regulation of protein phosphorylationIEAbiological_process
GO:0003779Actin bindingIEAmolecular_function
GO:0004864Protein phosphatase inhibitor activityNASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005654NucleoplasmIMPcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005912Adherens junctionIEAcellular_component
GO:0007015Actin filament organizationIEAbiological_process
GO:0007050Cell cycle arrestTASbiological_process
GO:0007096Regulation of exit from mitosisNASbiological_process
GO:0008157Protein phosphatase 1 bindingNASmolecular_function
GO:0008380RNA splicingNASbiological_process
GO:0016358Dendrite developmentIEAbiological_process
GO:0016477Cell migrationIMPbiological_process
GO:0019722Calcium-mediated signalingIEAbiological_process
GO:0030027LamellipodiumIDAcellular_component
GO:0030175FilopodiumIDAcellular_component
GO:0030308Negative regulation of cell growthIDAbiological_process
GO:0030864Cortical actin cytoskeletonIEAcellular_component
GO:0032587Ruffle membraneIDAcellular_component
GO:0042127Regulation of cell proliferationNASbiological_process
GO:0043086Negative regulation of catalytic activityNASbiological_process
GO:0043197Dendritic spineIEAcellular_component
GO:0045202SynapseIEAcellular_component
GO:0046847Filopodium assemblyIMPbiological_process
GO:0050790Regulation of catalytic activityNASbiological_process
GO:0071315Cellular response to morphineISSbiological_process
GO:2000474Regulation of opioid receptor signaling pathwayISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.18834032140.84275046920.84563767701.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0528870914
GSE13712_SHEARUp0.4357309962
GSE13712_STATICUp0.1522783290
GSE19018Down-0.1916895990
GSE19899_A1Up0.0009368121
GSE19899_A2Up0.2750431568
PubMed_21979375_A1Down-0.2475184821
PubMed_21979375_A2Up0.3498635747
GSE35957Down-0.3934112460
GSE36640Up0.0033343926
GSE54402Up0.1818100139
GSE9593Down-0.0595558104
GSE43922Up0.0892633450
GSE24585Down-0.2423685536
GSE37065Down-0.0217652089
GSE28863_A1Up0.1919697583
GSE28863_A2Up0.1723466558
GSE28863_A3Up0.3768832572
GSE28863_A4Up0.1498472226
GSE48662Up0.2877065757

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-122-5pMIMAT0000421MIRT023305MicroarrayFunctional MTI (Weak)17612493
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.