HCSGD entry for KLF11
1. General information
| Official gene symbol | KLF11 |
|---|---|
| Entrez ID | 8462 |
| Gene full name | Kruppel-like factor 11 |
| Other gene symbols | FKLF FKLF1 MODY7 TIEG2 Tieg3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000083 | Regulation of transcription involved in G1/S transition of mitotic cell cycle | IDA | biological_process |
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0000981 | Sequence-specific DNA binding RNA polymerase II transcription factor activity | IDA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA TAS | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0008285 | Negative regulation of cell proliferation | IDA | biological_process |
| GO:0043065 | Positive regulation of apoptotic process | IDA | biological_process |
| GO:0044212 | Transcription regulatory region DNA binding | IDA | molecular_function |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:1901653 | Cellular response to peptide | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1056363588 | 0.4792975571 | 0.6747038583 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0055204297 |
| GSE13712_SHEAR | Down | -0.3550150551 |
| GSE13712_STATIC | Down | -0.3839800118 |
| GSE19018 | Up | 0.4806439855 |
| GSE19899_A1 | Up | 0.1762797187 |
| GSE19899_A2 | Down | -0.0765929166 |
| PubMed_21979375_A1 | Up | 0.6717542879 |
| PubMed_21979375_A2 | Up | 0.0789747198 |
| GSE35957 | Up | 0.1796026101 |
| GSE36640 | Up | 0.4052824236 |
| GSE54402 | Up | 0.0619886258 |
| GSE9593 | Up | 0.4502402831 |
| GSE43922 | Up | 0.0529048052 |
| GSE24585 | Down | -0.6778837620 |
| GSE37065 | Up | 0.1636536155 |
| GSE28863_A1 | Up | 0.2009809491 |
| GSE28863_A2 | Up | 0.7406891933 |
| GSE28863_A3 | Up | 0.0420032808 |
| GSE28863_A4 | Down | -0.2670217033 |
| GSE48662 | Down | -0.2957852302 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-429 | MIMAT0001536 | MIRT016644 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020284 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-200a-3p | MIMAT0000682 | MIRT020356 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-200c-3p | MIMAT0000617 | MIRT021077 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-141-3p | MIMAT0000432 | MIRT021660 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-200b-3p | MIMAT0000318 | MIRT024132 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT028132 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
