HCSGD entry for PARD6B
1. General information
| Official gene symbol | PARD6B |
|---|---|
| Entrez ID | 84612 |
| Gene full name | par-6 partitioning defective 6 homolog beta (C. elegans) |
| Other gene symbols | PAR6B |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IDA TAS | cellular_component |
| GO:0005923 | Tight junction | IDA | cellular_component |
| GO:0005938 | Cell cortex | IEA | cellular_component |
| GO:0006461 | Protein complex assembly | IDA | biological_process |
| GO:0007043 | Cell-cell junction assembly | TAS | biological_process |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0007163 | Establishment or maintenance of cell polarity | TAS | biological_process |
| GO:0007409 | Axonogenesis | TAS | biological_process |
| GO:0030334 | Regulation of cell migration | TAS | biological_process |
| GO:0034329 | Cell junction assembly | TAS | biological_process |
| GO:0043234 | Protein complex | IEA | cellular_component |
| GO:0045177 | Apical part of cell | IEA | cellular_component |
| GO:0045216 | Cell-cell junction organization | TAS | biological_process |
| GO:0051301 | Cell division | IEA | biological_process |
| GO:0070830 | Tight junction assembly | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0042126401 | 0.9931027659 | 0.1751672986 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1425161794 |
| GSE13712_SHEAR | Up | 0.0986414115 |
| GSE13712_STATIC | Up | 0.0842083380 |
| GSE19018 | Up | 0.2243412105 |
| GSE19899_A1 | Up | 0.5351811564 |
| GSE19899_A2 | Up | 1.2623512525 |
| PubMed_21979375_A1 | Up | 1.2578549370 |
| PubMed_21979375_A2 | Up | 1.6722764708 |
| GSE35957 | Up | 0.0467128008 |
| GSE36640 | Up | 0.5882591925 |
| GSE54402 | Up | 0.6531227129 |
| GSE9593 | Up | 0.0322209313 |
| GSE43922 | Up | 1.5555306852 |
| GSE24585 | Down | -0.1177119244 |
| GSE37065 | Up | 0.0227891225 |
| GSE28863_A1 | Down | -0.1147398666 |
| GSE28863_A2 | Up | 0.3463543587 |
| GSE28863_A3 | Up | 0.5126627163 |
| GSE28863_A4 | Up | 0.1755075362 |
| GSE48662 | Down | -0.1614864666 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-374b-5p | MIMAT0004955 | MIRT016066 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT016847 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-125a-5p | MIMAT0000443 | MIRT021299 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-1 | MIMAT0000416 | MIRT023510 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-18a-5p | MIMAT0000072 | MIRT031352 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
