HCSGD entry for TTF2
1. General information
| Official gene symbol | TTF2 |
|---|---|
| Entrez ID | 8458 |
| Gene full name | transcription termination factor, RNA polymerase II |
| Other gene symbols | HuF2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005681 | Spliceosomal complex | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006200 | ATP catabolic process | TAS | biological_process |
| GO:0006353 | DNA-templated transcription, termination | TAS | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006369 | Termination of RNA polymerase II transcription | TAS | biological_process |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0008023 | Transcription elongation factor complex | TAS | cellular_component |
| GO:0008026 | ATP-dependent helicase activity | IEA | molecular_function |
| GO:0008094 | DNA-dependent ATPase activity | TAS | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0008380 | RNA splicing | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9754380305 | 0.0076869382 | 0.9999902473 | 0.1753230303 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3315570849 |
| GSE13712_SHEAR | Up | 0.3635705814 |
| GSE13712_STATIC | Up | 0.2495978475 |
| GSE19018 | Down | -0.2501464509 |
| GSE19899_A1 | Down | -0.2400327833 |
| GSE19899_A2 | Down | -0.5928762256 |
| PubMed_21979375_A1 | Down | -0.7330013211 |
| PubMed_21979375_A2 | Down | -0.9497726933 |
| GSE35957 | Down | -0.1313607652 |
| GSE36640 | Down | -1.0498604641 |
| GSE54402 | Down | -0.3637999721 |
| GSE9593 | Down | -0.0562353783 |
| GSE43922 | Down | -0.8497854896 |
| GSE24585 | Down | -0.5296889362 |
| GSE37065 | Down | -0.2648025786 |
| GSE28863_A1 | Up | 0.0207072758 |
| GSE28863_A2 | Up | 0.5787650364 |
| GSE28863_A3 | Down | -0.3337916674 |
| GSE28863_A4 | Down | -0.1220455890 |
| GSE48662 | Down | -0.5396777337 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024886 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026820 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT032032 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-183-5p | MIMAT0000261 | MIRT047031 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
