HCSGD entry for ZC3H8

1. General information

Official gene symbolZC3H8
Entrez ID84524
Gene full namezinc finger CCCH-type containing 8
Other gene symbolsFliz1 ZC3HDC8
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003700Sequence-specific DNA binding transcription factor activityIMPmolecular_function
GO:0003723RNA bindingIEAmolecular_function
GO:0005634NucleusISScellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006915Apoptotic processIEAbiological_process
GO:0033085Negative regulation of T cell differentiation in thymusIMPbiological_process
GO:0043029T cell homeostasisIMPbiological_process
GO:0043565Sequence-specific DNA bindingISSmolecular_function
GO:0045892Negative regulation of transcription, DNA-templatedIDA ISSbiological_process
GO:0046677Response to antibioticIDAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0070245Positive regulation of thymocyte apoptotic processIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03936996310.98382410240.44664683331.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2103920899
GSE13712_SHEARUp0.3285573477
GSE13712_STATICUp0.3234582097
GSE19018Down-0.1220945727
GSE19899_A1Up0.2579383798
GSE19899_A2Up0.6363318638
PubMed_21979375_A1Up0.6431722024
PubMed_21979375_A2Up0.5612803086
GSE35957Up0.0077735051
GSE36640Up0.0332700658
GSE54402Up0.0635667108
GSE9593Up0.1451786384
GSE43922Up0.2705277018
GSE24585Up0.1462546345
GSE37065Up0.1357516401
GSE28863_A1Up0.1382875211
GSE28863_A2Up0.5433491336
GSE28863_A3Down-0.0092514744
GSE28863_A4Down-0.1294422767
GSE48662Down-0.0039716661

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-186-5pMIMAT0000456MIRT044954CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.