HCSGD entry for DOC2A


1. General information

Official gene symbolDOC2A
Entrez ID8448
Gene full namedouble C2-like domains, alpha
Other gene symbolsDoc2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005215Transporter activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005544Calcium-dependent phospholipid bindingIEAmolecular_function
GO:0005764LysosomeIEAcellular_component
GO:0007268Synaptic transmissionTASbiological_process
GO:0007399Nervous system developmentTASbiological_process
GO:0008021Synaptic vesicleIEAcellular_component
GO:0016020MembraneIEAcellular_component
GO:0016079Synaptic vesicle exocytosisIEAbiological_process
GO:0017158Regulation of calcium ion-dependent exocytosisIMPbiological_process
GO:0030054Cell junctionIEAcellular_component
GO:0030672Synaptic vesicle membraneIEAcellular_component
GO:0043005Neuron projectionIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.53439745070.88731787930.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0025287715
GSE13712_SHEARUp0.0699363287
GSE13712_STATICUp0.1194024340
GSE19018Up0.0162804019
GSE19899_A1Down-0.0269979902
GSE19899_A2Up0.0139751203
PubMed_21979375_A1Down-0.1142849322
PubMed_21979375_A2Up0.1001252344
GSE35957Up0.0800235574
GSE36640Down-0.0084270286
GSE54402Up0.0372107685
GSE9593Down-0.0926611484
GSE43922Up0.1211919159
GSE24585Up0.3159703907
GSE37065Down-0.0257150710
GSE28863_A1Down-0.0618129891
GSE28863_A2Down-0.0062048989
GSE28863_A3Up0.3965131675
GSE28863_A4Up0.0445217133
GSE48662Down-0.0433871679

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.