HCSGD entry for DOC2B
1. General information
| Official gene symbol | DOC2B |
|---|---|
| Entrez ID | 8447 |
| Gene full name | double C2-like domains, beta |
| Other gene symbols | DOC2BL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005215 | Transporter activity | IEA | molecular_function |
| GO:0005544 | Calcium-dependent phospholipid binding | ISS | molecular_function |
| GO:0005737 | Cytoplasm | ISS | cellular_component |
| GO:0005886 | Plasma membrane | ISS | cellular_component |
| GO:0008021 | Synaptic vesicle | IEA | cellular_component |
| GO:0008104 | Protein localization | ISS | biological_process |
| GO:0015630 | Microtubule cytoskeleton | IDA | cellular_component |
| GO:0019905 | Syntaxin binding | IEA | molecular_function |
| GO:0031201 | SNARE complex | ISS | cellular_component |
| GO:0031340 | Positive regulation of vesicle fusion | ISS | biological_process |
| GO:0032024 | Positive regulation of insulin secretion | ISS | biological_process |
| GO:0045956 | Positive regulation of calcium ion-dependent exocytosis | ISS | biological_process |
| GO:0048791 | Calcium ion-dependent exocytosis of neurotransmitter | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7313027241 | 0.2990821207 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1318163872 |
| GSE13712_SHEAR | Down | -0.1507785881 |
| GSE13712_STATIC | Down | -0.2535762902 |
| GSE19018 | Up | 0.4359183498 |
| GSE19899_A1 | Down | -0.1364540274 |
| GSE19899_A2 | Up | 0.2220155325 |
| PubMed_21979375_A1 | Down | -0.1348990065 |
| PubMed_21979375_A2 | Down | -0.2041291034 |
| GSE35957 | Down | -0.0575878563 |
| GSE36640 | Down | -0.1110010918 |
| GSE54402 | Down | -0.0522190238 |
| GSE9593 | Down | -0.0375615231 |
| GSE43922 | Down | -0.0652946532 |
| GSE24585 | Up | 0.0250320063 |
| GSE37065 | Down | -0.0602119701 |
| GSE28863_A1 | Down | -0.2059148218 |
| GSE28863_A2 | Down | -0.2528413212 |
| GSE28863_A3 | Up | 0.4179057421 |
| GSE28863_A4 | Up | 0.1595483368 |
| GSE48662 | Up | 0.0729252796 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
