HCSGD entry for DYRK3
1. General information
| Official gene symbol | DYRK3 |
|---|---|
| Entrez ID | 8444 |
| Gene full name | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| Other gene symbols | DYRK5 RED REDK hYAK3-2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000287 | Magnesium ion binding | IDA | molecular_function |
| GO:0004672 | Protein kinase activity | IDA IEA | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0004712 | Protein serine/threonine/tyrosine kinase activity | IEA | molecular_function |
| GO:0004713 | Protein tyrosine kinase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IDA IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0006468 | Protein phosphorylation | IDA | biological_process |
| GO:0030218 | Erythrocyte differentiation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0266639565 | 0.9341787356 | 0.3803090466 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4276411140 |
| GSE13712_SHEAR | Up | 0.2109922359 |
| GSE13712_STATIC | Up | 0.4011272629 |
| GSE19018 | Up | 0.1855010742 |
| GSE19899_A1 | Up | 0.3740694308 |
| GSE19899_A2 | Up | 0.5859220731 |
| PubMed_21979375_A1 | Up | 0.7357347215 |
| PubMed_21979375_A2 | Up | 0.5151652671 |
| GSE35957 | Down | -0.0316024725 |
| GSE36640 | Up | 0.1252360347 |
| GSE54402 | Up | 0.3595601692 |
| GSE9593 | Up | 0.2028356237 |
| GSE43922 | Up | 0.7727284981 |
| GSE24585 | Down | -0.0401960786 |
| GSE37065 | Up | 0.1923490562 |
| GSE28863_A1 | Down | -0.4934982843 |
| GSE28863_A2 | Up | 0.1734606471 |
| GSE28863_A3 | Down | -0.7540107612 |
| GSE28863_A4 | Down | -0.0722212418 |
| GSE48662 | Down | -0.0697966680 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029437 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
