HCSGD entry for CASQ1
1. General information
| Official gene symbol | CASQ1 |
|---|---|
| Entrez ID | 844 |
| Gene full name | calsequestrin 1 (fast-twitch, skeletal muscle) |
| Other gene symbols | CASQ PDIB1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0005783 | Endoplasmic reticulum | NAS | cellular_component |
| GO:0005790 | Smooth endoplasmic reticulum | TAS | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0007029 | Endoplasmic reticulum organization | IEA | biological_process |
| GO:0007519 | Skeletal muscle tissue development | IEA | biological_process |
| GO:0009408 | Response to heat | IEA | biological_process |
| GO:0010033 | Response to organic substance | IEA | biological_process |
| GO:0014804 | Terminal cisterna lumen | IEA | cellular_component |
| GO:0014809 | Regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion | IEA | biological_process |
| GO:0014894 | Response to denervation involved in regulation of muscle adaptation | IEA | biological_process |
| GO:0030315 | T-tubule | IEA | cellular_component |
| GO:0031674 | I band | IEA | cellular_component |
| GO:0033017 | Sarcoplasmic reticulum membrane | TAS | cellular_component |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0051282 | Regulation of sequestering of calcium ion | IEA | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8021066981 | 0.6149613541 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0501317249 |
| GSE13712_SHEAR | Down | -0.1000370341 |
| GSE13712_STATIC | Up | 0.0103448331 |
| GSE19018 | Up | 0.1405628753 |
| GSE19899_A1 | Up | 0.0986943768 |
| GSE19899_A2 | Down | -0.1123373099 |
| PubMed_21979375_A1 | Up | 0.0471044640 |
| PubMed_21979375_A2 | Up | 0.0264967963 |
| GSE35957 | Up | 0.0675260739 |
| GSE36640 | Down | -0.1208484213 |
| GSE54402 | Up | 0.1245273948 |
| GSE9593 | Up | 0.0798954921 |
| GSE43922 | Up | 0.0200603359 |
| GSE24585 | Up | 0.0663979085 |
| GSE37065 | Down | -0.1736475324 |
| GSE28863_A1 | Down | -0.2662487635 |
| GSE28863_A2 | Down | -0.0580069067 |
| GSE28863_A3 | Up | 0.2102586560 |
| GSE28863_A4 | Down | -0.0550649856 |
| GSE48662 | Down | -0.0626767088 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018690 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029942 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
