HCSGD entry for RAD54L
1. General information
| Official gene symbol | RAD54L |
|---|---|
| Entrez ID | 8438 |
| Gene full name | RAD54-like (S. cerevisiae) |
| Other gene symbols | HR54 RAD54A hHR54 hRAD54 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000724 | Double-strand break repair via homologous recombination | IEA | biological_process |
| GO:0000733 | DNA strand renaturation | IDA | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0004386 | Helicase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006281 | DNA repair | TAS | biological_process |
| GO:0006310 | DNA recombination | TAS | biological_process |
| GO:0007126 | Meiosis | TAS | biological_process |
| GO:0010212 | Response to ionizing radiation | IEA | biological_process |
| GO:0036310 | Annealing helicase activity | IDA | molecular_function |
| GO:0042493 | Response to drug | IEA | biological_process |
| GO:0051276 | Chromosome organization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9629853463 | 0.0054324570 | 0.9999902473 | 0.1494124347 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0604248093 |
| GSE13712_SHEAR | Up | 0.0899518366 |
| GSE13712_STATIC | Up | 0.1985896014 |
| GSE19018 | Up | 0.0981254442 |
| GSE19899_A1 | Down | -0.2242823627 |
| GSE19899_A2 | Down | -2.1192618479 |
| PubMed_21979375_A1 | Down | -0.9087529442 |
| PubMed_21979375_A2 | Down | -0.8863471120 |
| GSE35957 | Down | -0.6723797267 |
| GSE36640 | Down | -2.5614141252 |
| GSE54402 | Down | -0.3608668185 |
| GSE9593 | Down | -0.4949297774 |
| GSE43922 | Down | -0.4718869540 |
| GSE24585 | Down | -0.1063602311 |
| GSE37065 | Down | -0.1884712755 |
| GSE28863_A1 | Down | -0.0325217042 |
| GSE28863_A2 | Up | 0.5606333285 |
| GSE28863_A3 | Up | 0.0723291822 |
| GSE28863_A4 | Up | 0.0661140095 |
| GSE48662 | Down | -1.6222421776 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028893 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-146a-5p | MIMAT0000449 | NA | hsa-miR-146a | 19944095 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
