HCSGD entry for RASAL1
1. General information
| Official gene symbol | RASAL1 |
|---|---|
| Entrez ID | 8437 |
| Gene full name | RAS protein activator like 1 (GAP1 like) |
| Other gene symbols | RASAL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005099 | Ras GTPase activator activity | IBA | molecular_function |
| GO:0005543 | Phospholipid binding | TAS | molecular_function |
| GO:0005737 | Cytoplasm | IBA | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0031235 | Intrinsic component of the cytoplasmic side of the plasma membrane | IBA | cellular_component |
| GO:0032320 | Positive regulation of Ras GTPase activity | IBA | biological_process |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0046580 | Negative regulation of Ras protein signal transduction | IBA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8696232590 | 0.5081977926 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0628424133 |
| GSE13712_SHEAR | Down | -0.0060283457 |
| GSE13712_STATIC | Down | -0.0566405323 |
| GSE19018 | Up | 0.0855814005 |
| GSE19899_A1 | Up | 0.0458237171 |
| GSE19899_A2 | Up | 0.0315998675 |
| PubMed_21979375_A1 | Up | 0.1038834031 |
| PubMed_21979375_A2 | Down | -0.2072402600 |
| GSE35957 | Up | 0.1451050997 |
| GSE36640 | Down | -0.0391076045 |
| GSE54402 | Down | -0.0911517567 |
| GSE9593 | Down | -0.0975449544 |
| GSE43922 | Down | -0.0016649862 |
| GSE24585 | Down | -0.1558704566 |
| GSE37065 | Down | -0.0779745416 |
| GSE28863_A1 | Down | -0.0890551527 |
| GSE28863_A2 | Down | -0.0560860457 |
| GSE28863_A3 | Up | 0.2701829662 |
| GSE28863_A4 | Up | 0.1429543631 |
| GSE48662 | Down | -0.1502051482 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-421 | MIMAT0003339 | MIRT039442 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
