HCSGD entry for STK24
1. General information
| Official gene symbol | STK24 |
|---|---|
| Entrez ID | 8428 |
| Gene full name | serine/threonine kinase 24 |
| Other gene symbols | MST3 MST3B STE20 STK3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004672 | Protein kinase activity | IEA TAS | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IDA | molecular_function |
| GO:0004702 | Receptor signaling protein serine/threonine kinase activity | IBA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006468 | Protein phosphorylation | IDA | biological_process |
| GO:0006915 | Apoptotic process | TAS | biological_process |
| GO:0006921 | Cellular component disassembly involved in execution phase of apoptosis | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0008631 | Intrinsic apoptotic signaling pathway in response to oxidative stress | IMP | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0023014 | Signal transduction by phosphorylation | IBA | biological_process |
| GO:0030336 | Negative regulation of cell migration | IMP | biological_process |
| GO:0046777 | Protein autophosphorylation | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0048679 | Regulation of axon regeneration | IMP | biological_process |
| GO:0097194 | Execution phase of apoptosis | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3228583261 | 0.8262650697 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1241879342 |
| GSE13712_SHEAR | Up | 0.0405852692 |
| GSE13712_STATIC | Down | -0.0529074649 |
| GSE19018 | Down | -0.0568679074 |
| GSE19899_A1 | Up | 0.2253178650 |
| GSE19899_A2 | Up | 0.2501864368 |
| PubMed_21979375_A1 | Up | 0.2139182359 |
| PubMed_21979375_A2 | Up | 0.2792747399 |
| GSE35957 | Down | -0.2074894661 |
| GSE36640 | Down | -0.1218433168 |
| GSE54402 | Up | 0.1809021182 |
| GSE9593 | Up | 0.0332718064 |
| GSE43922 | Up | 0.1811392745 |
| GSE24585 | Down | -0.0527241552 |
| GSE37065 | Down | -0.0126566071 |
| GSE28863_A1 | Up | 0.4143984517 |
| GSE28863_A2 | Down | -0.4077521686 |
| GSE28863_A3 | Up | 0.0175998100 |
| GSE28863_A4 | Up | 0.0730479022 |
| GSE48662 | Down | -0.1500615037 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020540 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT023521 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036877 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045062 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
