HCSGD entry for LTBP4

1. General information

Official gene symbolLTBP4
Entrez ID8425
Gene full namelatent transforming growth factor beta binding protein 4
Other gene symbolsARCL1C LTBP-4 LTBP4L LTBP4S
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001558Regulation of cell growthTASbiological_process
GO:0005024Transforming growth factor beta-activated receptor activityNASmolecular_function
GO:0005178Integrin bindingNASmolecular_function
GO:0005509Calcium ion bindingIEA NASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005539Glycosaminoglycan bindingNASmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005578Proteinaceous extracellular matrixIDAcellular_component
GO:0005615Extracellular spaceIDAcellular_component
GO:0006457Protein foldingTASbiological_process
GO:0006468Protein phosphorylationNASbiological_process
GO:0007179Transforming growth factor beta receptor signaling pathwayIEAbiological_process
GO:0007275Multicellular organismal developmentTASbiological_process
GO:0016310PhosphorylationNASbiological_process
GO:0017015Regulation of transforming growth factor beta receptor signaling pathwayTASbiological_process
GO:0030162Regulation of proteolysisIDAbiological_process
GO:0030198Extracellular matrix organizationTASbiological_process
GO:0030252Growth hormone secretionTASbiological_process
GO:0031012Extracellular matrixIDAcellular_component
GO:0045595Regulation of cell differentiationTASbiological_process
GO:0050431Transforming growth factor beta bindingIDAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.54251340370.08595726230.99999024730.5573986450

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1214478660
GSE13712_SHEARDown-0.7728669757
GSE13712_STATICDown-0.4046182670
GSE19018Up0.0810897842
GSE19899_A1Down-0.1312330949
GSE19899_A2Down-0.3783947182
PubMed_21979375_A1Down-0.5906508371
PubMed_21979375_A2Down-0.1928660094
GSE35957Down-0.2254387120
GSE36640Down-0.0955564918
GSE54402Down-0.5274506229
GSE9593Up0.0420517533
GSE43922Down-0.4959841724
GSE24585Up0.6489215131
GSE37065Down-0.2527349033
GSE28863_A1Up0.8334322479
GSE28863_A2Up0.5230890212
GSE28863_A3Up0.2860121792
GSE28863_A4Up0.0155079373
GSE48662Up0.2060565138

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017571MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.