HCSGD entry for BBOX1
1. General information
| Official gene symbol | BBOX1 |
|---|---|
| Entrez ID | 8424 |
| Gene full name | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 |
| Other gene symbols | BBH BBOX G-BBH gamma-BBH |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005506 | Iron ion binding | IEA | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0008270 | Zinc ion binding | IDA | molecular_function |
| GO:0008336 | Gamma-butyrobetaine dioxygenase activity | IDA ISS TAS | molecular_function |
| GO:0015629 | Actin cytoskeleton | IDA | cellular_component |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0045329 | Carnitine biosynthetic process | IDA IEA TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5125375366 | 0.8491681319 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2404928431 |
| GSE13712_SHEAR | Down | -0.2470083067 |
| GSE13712_STATIC | Down | -0.0916591905 |
| GSE19018 | Up | 0.0376030289 |
| GSE19899_A1 | Down | -0.0138343789 |
| GSE19899_A2 | Up | 0.0192534785 |
| PubMed_21979375_A1 | Up | 0.3578078947 |
| PubMed_21979375_A2 | Up | 0.2035823246 |
| GSE35957 | Up | 0.1476405007 |
| GSE36640 | Up | 0.2379311989 |
| GSE54402 | Down | -0.0554719629 |
| GSE9593 | Down | -0.4713280512 |
| GSE43922 | Up | 0.0210898847 |
| GSE24585 | Up | 0.0850414047 |
| GSE37065 | Up | 0.0596158537 |
| GSE28863_A1 | Up | 0.0465551369 |
| GSE28863_A2 | Up | 0.0776092411 |
| GSE28863_A3 | Up | 0.1454364258 |
| GSE28863_A4 | Down | -0.0421055990 |
| GSE48662 | Down | -0.0049387736 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Vitamin C | DB00126 | NUTR00001 | APRD00084 | EXPT00568 | DB09541 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
