HCSGD entry for TRAF7
1. General information
| Official gene symbol | TRAF7 |
|---|---|
| Entrez ID | 84231 |
| Gene full name | TNF receptor-associated factor 7, E3 ubiquitin protein ligase |
| Other gene symbols | RFWD1 RNF119 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000151 | Ubiquitin ligase complex | IDA | cellular_component |
| GO:0000185 | Activation of MAPKKK activity | IDA | biological_process |
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006915 | Apoptotic process | IDA | biological_process |
| GO:0008270 | Zinc ion binding | NAS | molecular_function |
| GO:0016023 | Cytoplasmic membrane-bounded vesicle | IEA | cellular_component |
| GO:0016567 | Protein ubiquitination | IDA | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0043410 | Positive regulation of MAPK cascade | IDA | biological_process |
| GO:0097194 | Execution phase of apoptosis | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3003538049 | 0.5345958512 | 0.9988275631 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0904546950 |
| GSE13712_SHEAR | Down | -0.1614188557 |
| GSE13712_STATIC | Down | -0.2063142759 |
| GSE19018 | Up | 0.1138407189 |
| GSE19899_A1 | Up | 0.0590905177 |
| GSE19899_A2 | Up | 0.2729377483 |
| PubMed_21979375_A1 | Down | -0.1730794263 |
| PubMed_21979375_A2 | Up | 0.6415409806 |
| GSE35957 | Up | 0.0328777125 |
| GSE36640 | Up | 0.1095012883 |
| GSE54402 | Up | 0.0860122209 |
| GSE9593 | Down | -0.0208588929 |
| GSE43922 | Up | 0.4437882931 |
| GSE24585 | Down | -0.8342840426 |
| GSE37065 | Down | -0.2680044151 |
| GSE28863_A1 | Up | 0.3563087994 |
| GSE28863_A2 | Up | 0.0647806799 |
| GSE28863_A3 | Down | -0.0593207881 |
| GSE28863_A4 | Down | -0.0681146916 |
| GSE48662 | Up | 0.2088344794 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-484 | MIMAT0002174 | MIRT042237 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052480 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
