HCSGD entry for SLA2

1. General information

Official gene symbolSLA2
Entrez ID84174
Gene full nameSrc-like-adaptor 2
Other gene symbolsC20orf156 MARS SLAP-2 SLAP2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0005070SH3/SH2 adaptor activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmTAScellular_component
GO:0005770Late endosomeIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0009967Positive regulation of signal transductionIDAbiological_process
GO:0010008Endosome membraneNAScellular_component
GO:0016023Cytoplasmic membrane-bounded vesicleIEAcellular_component
GO:0019724B cell mediated immunityTASbiological_process
GO:0030522Intracellular receptor signaling pathwayTASbiological_process
GO:0042110T cell activationTASbiological_process
GO:0047485Protein N-terminus bindingIPImolecular_function
GO:0050776Regulation of immune responseNASbiological_process
GO:0050849Negative regulation of calcium-mediated signalingIDAbiological_process
GO:0050851Antigen receptor-mediated signaling pathwayTASbiological_process
GO:0050869Negative regulation of B cell activationTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.96090322940.32509616280.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1140177547
GSE13712_SHEARDown-0.1128546715
GSE13712_STATICDown-0.1447895877
GSE19018Down-0.0256727018
GSE19899_A1Down-0.0242084661
GSE19899_A2Down-0.0265236540
PubMed_21979375_A1Down-0.1053632910
PubMed_21979375_A2Down-0.1159654328
GSE35957Up0.1399128977
GSE36640Up0.0161887517
GSE54402Down-0.0044768345
GSE9593Down-0.0888461237
GSE43922Up0.0246967376
GSE24585Down-0.0569106102
GSE37065Up0.0567349808
GSE28863_A1Down-0.1437969749
GSE28863_A2Down-0.3437594017
GSE28863_A3Up0.0299427851
GSE28863_A4Up0.0006891630
GSE48662Down-0.0243728447

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018729MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.