HCSGD entry for ANTXR1
1. General information
| Official gene symbol | ANTXR1 |
|---|---|
| Entrez ID | 84168 |
| Gene full name | anthrax toxin receptor 1 |
| Other gene symbols | ATR TEM8 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004872 | Receptor activity | IEA | molecular_function |
| GO:0004888 | Transmembrane signaling receptor activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005518 | Collagen binding | IDA | molecular_function |
| GO:0007165 | Signal transduction | IDA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0022414 | Reproductive process | IEA | biological_process |
| GO:0031258 | Lamellipodium membrane | IDA | cellular_component |
| GO:0031527 | Filopodium membrane | IDA | cellular_component |
| GO:0031532 | Actin cytoskeleton reorganization | IDA | biological_process |
| GO:0034446 | Substrate adhesion-dependent cell spreading | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0051015 | Actin filament binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1609361043 | 0.3315269747 | 0.7951118784 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3021196558 |
| GSE13712_SHEAR | Down | -0.3883904449 |
| GSE13712_STATIC | Down | -0.0420676880 |
| GSE19018 | Down | -0.4244835814 |
| GSE19899_A1 | Down | -0.0017392409 |
| GSE19899_A2 | Up | 0.4512938942 |
| PubMed_21979375_A1 | Down | -0.3917126119 |
| PubMed_21979375_A2 | Up | 0.5028330229 |
| GSE35957 | Up | 0.8708616478 |
| GSE36640 | Up | 1.1873027007 |
| GSE54402 | Down | -0.2389838278 |
| GSE9593 | Up | 0.2603374134 |
| GSE43922 | Down | -0.1526909395 |
| GSE24585 | Down | -0.1076352233 |
| GSE37065 | Up | 0.3160103490 |
| GSE28863_A1 | Up | 0.1716551729 |
| GSE28863_A2 | Up | 0.1665297541 |
| GSE28863_A3 | Up | 0.1925923130 |
| GSE28863_A4 | Down | -0.2538029759 |
| GSE48662 | Up | 0.3046342475 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020976 | Proteomics | Functional MTI (Weak) | 20584899 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020976 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052106 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
