HCSGD entry for PCGF6
1. General information
| Official gene symbol | PCGF6 |
|---|---|
| Entrez ID | 84108 |
| Gene full name | polycomb group ring finger 6 |
| Other gene symbols | MBLR RNF134 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0031519 | PcG protein complex | IDA TAS | cellular_component |
| GO:0035102 | PRC1 complex | IDA | cellular_component |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7524351772 | 0.0514168421 | 0.9999902473 | 0.4262496693 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1192595185 |
| GSE13712_SHEAR | Down | -0.1170180203 |
| GSE13712_STATIC | Up | 0.0107529035 |
| GSE19018 | Down | -0.2663678672 |
| GSE19899_A1 | Up | 0.0567273083 |
| GSE19899_A2 | Down | -0.3660609416 |
| PubMed_21979375_A1 | Up | 0.5037146402 |
| PubMed_21979375_A2 | Up | 0.1243271491 |
| GSE35957 | Down | -0.4196469500 |
| GSE36640 | Down | -1.0520945390 |
| GSE54402 | Up | 0.2853554263 |
| GSE9593 | Down | -0.5935950819 |
| GSE43922 | Up | 0.0815242871 |
| GSE24585 | Down | -0.5047556081 |
| GSE37065 | Down | -0.1240002852 |
| GSE28863_A1 | Down | -0.0272597508 |
| GSE28863_A2 | Down | -0.0064195614 |
| GSE28863_A3 | Down | -0.1235209896 |
| GSE28863_A4 | Up | 0.2004956196 |
| GSE48662 | Down | -0.7866534912 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-24-3p | MIMAT0000080 | MIRT030560 | Microarray | Functional MTI (Weak) | 19748357 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
