HCSGD entry for UXT
1. General information
| Official gene symbol | UXT |
|---|---|
| Entrez ID | 8409 |
| Gene full name | ubiquitously-expressed, prefoldin-like chaperone |
| Other gene symbols | ART-27 STAP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0000226 | Microtubule cytoskeleton organization | IMP | biological_process |
| GO:0000930 | Gamma-tubulin complex | IDA | cellular_component |
| GO:0001106 | RNA polymerase II transcription corepressor activity | IDA | molecular_function |
| GO:0003682 | Chromatin binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005856 | Cytoskeleton | IDA | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0006457 | Protein folding | IEA | biological_process |
| GO:0008017 | Microtubule binding | TAS | molecular_function |
| GO:0016272 | Prefoldin complex | IEA | cellular_component |
| GO:0047497 | Mitochondrion transport along microtubule | TAS | biological_process |
| GO:0048487 | Beta-tubulin binding | IDA | molecular_function |
| GO:0051015 | Actin filament binding | IDA | molecular_function |
| GO:0051082 | Unfolded protein binding | IEA | molecular_function |
| GO:0051297 | Centrosome organization | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9719374530 | 0.0181583147 | 0.9999902473 | 0.2636210700 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1125580096 |
| GSE13712_SHEAR | Down | -0.3747821980 |
| GSE13712_STATIC | Down | -0.3363322605 |
| GSE19018 | Up | 0.1419643557 |
| GSE19899_A1 | Down | -0.7882799278 |
| GSE19899_A2 | Down | -0.3321692864 |
| PubMed_21979375_A1 | Up | 0.6747090028 |
| PubMed_21979375_A2 | Up | 0.1014045193 |
| GSE35957 | Down | -0.5451969466 |
| GSE36640 | Down | -0.4626308778 |
| GSE54402 | Up | 0.2245971259 |
| GSE9593 | Up | 0.1073667332 |
| GSE43922 | Down | -0.4567885166 |
| GSE24585 | Down | -0.2693513464 |
| GSE37065 | Down | -0.3239491713 |
| GSE28863_A1 | Down | -0.3302309740 |
| GSE28863_A2 | Down | -0.6203836527 |
| GSE28863_A3 | Down | -0.2393946810 |
| GSE28863_A4 | Down | -0.0627034380 |
| GSE48662 | Down | -0.2338218173 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029970 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031877 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045646 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047919 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
