HCSGD entry for PIP4K2B
1. General information
| Official gene symbol | PIP4K2B |
|---|---|
| Entrez ID | 8396 |
| Gene full name | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| Other gene symbols | PI5P4KB PIP5K2B PIP5KIIB PIP5KIIbeta |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005057 | Receptor signaling protein activity | TAS | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006661 | Phosphatidylinositol biosynthetic process | TAS | biological_process |
| GO:0007166 | Cell surface receptor signaling pathway | TAS | biological_process |
| GO:0016307 | Phosphatidylinositol phosphate kinase activity | IEA | molecular_function |
| GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity | IDA | molecular_function |
| GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity | IEA | molecular_function |
| GO:0035556 | Intracellular signal transduction | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046854 | Phosphatidylinositol phosphorylation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5316060978 | 0.6567687360 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0443386736 |
| GSE13712_SHEAR | Up | 0.2586182941 |
| GSE13712_STATIC | Down | -0.0470593736 |
| GSE19018 | Down | -0.0652725419 |
| GSE19899_A1 | Up | 0.1127465925 |
| GSE19899_A2 | Up | 0.4342996253 |
| PubMed_21979375_A1 | Down | -0.3181697875 |
| PubMed_21979375_A2 | Up | 0.1295131608 |
| GSE35957 | Up | 0.1924941050 |
| GSE36640 | Up | 0.3471622921 |
| GSE54402 | Up | 0.0507512172 |
| GSE9593 | Up | 0.1237963516 |
| GSE43922 | Down | -0.0510548123 |
| GSE24585 | Up | 0.0252102818 |
| GSE37065 | Down | -0.2003564009 |
| GSE28863_A1 | Down | -0.1308505225 |
| GSE28863_A2 | Up | 0.2074644522 |
| GSE28863_A3 | Down | -0.7199021984 |
| GSE28863_A4 | Up | 0.0067769462 |
| GSE48662 | Up | 0.1794861401 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-186-5p | MIMAT0000456 | MIRT021118 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024431 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026451 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-99b-5p | MIMAT0000689 | MIRT044205 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044592 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051101 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
