HCSGD entry for KCTD10


1. General information

Official gene symbolKCTD10
Entrez ID83892
Gene full namepotassium channel tetramerisation domain containing 10
Other gene symbolsBTBD28 ULRO61 hBACURD3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004842Ubiquitin-protein ligase activityISSmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0016567Protein ubiquitinationISSbiological_process
GO:0031463Cul3-RING ubiquitin ligase complexISScellular_component
GO:0036038TCTN-B9D complexIEAcellular_component
GO:0043161Proteasome-mediated ubiquitin-dependent protein catabolic processISSbiological_process
GO:0051260Protein homooligomerizationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.19856604990.56833324340.86093453561.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1782144305
GSE13712_SHEARDown-0.0733440237
GSE13712_STATICDown-0.1740313914
GSE19018Down-0.2402007381
GSE19899_A1Down-0.3565786834
GSE19899_A2Up0.3062098386
PubMed_21979375_A1Up0.0094880359
PubMed_21979375_A2Up0.4702874259
GSE35957Up0.4199901748
GSE36640Up0.1287805691
GSE54402Up0.5549726486
GSE9593Up0.5072174565
GSE43922Down-0.0337976928
GSE24585Up0.1001015000
GSE37065Down-0.3126333835
GSE28863_A1Up0.7166672086
GSE28863_A2Up0.2508244319
GSE28863_A3Down-0.0366105326
GSE28863_A4Up0.0145204352
GSE48662Down-0.1408078998

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-375MIMAT0000728MIRT019854MicroarrayFunctional MTI (Weak)20215506
hsa-miR-130b-3pMIMAT0000691MIRT020169SequencingFunctional MTI (Weak)20371350
hsa-miR-19b-3pMIMAT0000074MIRT031145SequencingFunctional MTI (Weak)20371350
hsa-miR-193b-3pMIMAT0002819MIRT041231CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.